Pantoprazole Tablets IP (NKPRA-40)

Description

PRA-40 is a proton pump inhibitor (PPI) containing Pantoprazole, widely used for reducing stomach acid production and treating acid-related gastrointestinal disorders. It works by inhibiting the proton pumps in the stomach lining, thereby decreasing acid secretion and providing relief from conditions like GERD, ulcers, and Zollinger-Ellison syndrome.

Composition:

Pantoprazole Sodium Sesquihydrate 40 mg 
A potent acid-suppressing agent that blocks the final step of gastric acid production, leading to effective and long-lasting relief from acidity-related issues.

Indications:

PRA-40 is prescribed for the treatment of:

Acid-Related Disorders in Humans:

• Gastroesophageal Reflux Disease (GERD) – Chronic acid reflux causing heartburn and irritation.
• Peptic Ulcers – Stomach and duodenal ulcers caused by excess acid or H. pylori infection.
• Zollinger-Ellison Syndrome – A rare condition causing excessive acid secretion due to gastrin-secreting tumors.
• Erosive Esophagitis – Inflammation and damage to the esophagus caused by stomach acid.

Dosage & Administration:

• Route:Oral, to be taken before meals for maximum absorption.
• Dosage:
  • Adults: 40 mg once daily, or as directed by a physician.
  • Severe cases:May be increased to 80 mg per day under medical supervision.
  • Children (above 5 years): Dosage based on body weight and medical advice.

Precautions & Warnings:

• Not recommended for long-term use without a doctor’s supervision.
• Avoid in patients with severe liver disease unless prescribed with dose adjustments.
• May reduce calcium and magnesium absorption with prolonged use, leading to deficiencies.
• Should not be taken simultaneously with antacids, as they may reduce its effectiveness.
• Caution in pregnant and breastfeeding women, use only if essential.

Side Effects:

• Common: Headache, nausea, dizziness, diarrhea, constipation.
• Rare: Vitamin B12 deficiency (with long-term use), osteoporosis risk, kidney issues.
• Serious (but rare): Severe allergic reactions, difficulty breathing, irregular heartbeat.