Febuxostat Tablets 80 mg (Sanxo-80)

Sanxo-80 contains Febuxostat 80 mg, a xanthine oxidase inhibitor used to lower high levels of uric acid in the blood. It is primarily prescribed for patients suffering from gout and hyperuricemia, conditions caused by excessive uric acid buildup that leads to joint inflammation and pain.

Composition:

• Active Ingredient: Febuxostat 80 mg
• Excipients: Microcrystalline cellulose, magnesium stearate, lactose monohydrate, povidone, and other inactive ingredients.

Indications:

Sanxo-80 is recommended for:

• Gout: A type of arthritis caused by uric acid crystal deposition in the joints.
• Hyperuricemia: Elevated uric acid levels, particularly in patients with chronic kidney disease or undergoing chemotherapy.

How It Works:

Febuxostat works by inhibiting the enzyme xanthine oxidase, which is responsible for the production of uric acid. By reducing uric acid levels in the blood, it helps prevent gout attacks and joint inflammation.

Dosage & Administration:

• Usual Adult Dose: 80 mg once daily with or without food.
• Severe Cases: The dose may be increased to 120 mg per day under medical supervision.
• Administration: Take with a full glass of water, preferably at the same time each day.

Precautions & Warnings:

• Not recommended for patients with severe liver or kidney disease.
• May increase the risk of cardiovascular events (heart attack, stroke).
• Avoid use in pregnant and breastfeeding women unless prescribed by a doctor.
• Patients with a history of allergic reactions to Febuxostat should avoid taking this medication.

Side Effects:

Common side effects include:

• Mild: Headache, dizziness, nausea, joint pain, rash.
• Serious (Rare): Chest pain, liver enzyme abnormalities, shortness of breath, severe allergic reactions.

Drug Interactions:

• Avoid theophylline, azathioprine, and mercaptopurine, as Febuxostat may increase toxicity.
• Use caution with blood thinners (e.g., warfarin), as it may alter clotting time.

Storage Instructions:

• Store at room temperature (15°C – 30°C).
• Keep away from direct sunlight and moisture.
• Keep out of reach of children.

Conclusion:

Sanxo-80 (Febuxostat 80 mg) is an effective medication for managing high uric acid levels in gout and hyperuricemia. Regular monitoring and adherence to dosage instructions are crucial for safe and effective treatment. Always consult a doctor before starting or adjusting the dose.